What is the study about?
This is a clinical drug trial for people with diagnosis of Alzheimer’s who are experiencing agitation or aggression. Participants will be randomly chosen to receive Mirtazapine (which is a drug licenced in the UK but not commonly used for dementia) or a placebo for a period of 12 weeks.
Who can take part?
People with Alzheimer’s, who are experiencing any symptoms of agitation or aggression and have a carer or someone who can act as a study partner. The person will have had to be stable on dementia medication for 3 months prior to agreeing to take part. If someone does not have the capacity to give consent to take part then their legal representative will need to give consent, providing they know the person would have agreed to take part.
What is involved?
The study involves questionnaires, blood tests and an electrocardiogram (ECG). There will be three visits over the 12 weeks of the study, and all visits are done in the patient’s home, to minimise burden for carer and participant. There will also be three follow up calls at 16, 26 and 52 weeks.
How do I get involved?
For more information, please email the study co-ordinator, Mariana Gavrila, on firstname.lastname@example.org or ring 01932 723330.